The Science
Science Behind NanoPalm
NanoPalm's science combines AI-driven formulation design and nanocontact printing technology to manufacture patterned lipid nanoparticles with precision.
NanoPalm's science combines AI-driven formulation design and nanocontact printing technology to manufacture patterned lipid nanoparticles with precision.
From raw lipids to patterned LNPs — EnsaliX Chips are pre-formulated, AI-designed patterned lipids produced by nanocontact printing, engineered for stability, safety, and selectivity without ionizable lipids or active-targeting ligands.
EnsaliX predicts novel pLNP formulations based on the disease microenvironment — accelerating R&D and reducing trial-and-error experimentation.
Trained on a large LNP dataset using machine learning, computer vision, and predictive analytics. Predicts customized pLNP formulations for each payload, target tissue, and route.
→ Formulation recommendation + technical reportSemi-solid patterned lipid chips produced by nanocontact printing — controlling size, shape, and surface chemistry for consistency and stability.
→ Manufactured pLNP ChipsEnsaliX Chips formulate therapeutic doses with improved stability, safety, and self-targeting beyond the liver — no active targeting ligands.
→ pLNP ready for preclinical evaluationNanoPalm advances partnered programs through co-development collaborations with early adopters supporting clinical translation.
Stage progression: Discovery → Lead optimization → Preclinical → IND Studies
Explore the latest from NanoPalm — company news, press releases, and peer-reviewed research.