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Deep-Tech Nanomedicine

Nanoparticle 2.0 for Advanced Therapeutics

WE PARTNER.  WE ENABLE NEXT-GENERATION THERAPEUTICS.

NanoPalm engineers AI-designed patterned lipid nanoparticles that enable biotechnology and pharmaceutical partners to achieve more precise, scalable therapeutic delivery.

Key Pages

News, peer-reviewed research, and pLNP technology resources from NanoPalm.

Three Ways to Build With NanoPalm

From ready-to-use chips to full asset co-development — choose the engagement that fits your program.

AI plus Chips

NanoPalm's technology patterns lipid nanostructure directly onto a chip designed by our EnsaliX Platform. Our AI returns an optimized formulation to the exact specs submitted by our partner's target product profile for precise, efficient, and programmable delivery of advanced therapeutics.

AI-engineered design Patterned lipid nanoparticles on chips Therapeutic delivery Extra-hepatic targeting

DeepTech Precision Beyond Conventional LNPs

Comparison of conventional randomized lipid nanoparticles versus EnsaliX-designed patterned lipid nanoparticles
Conventional LNPs

Enabled breakthrough therapies, but limited by consistency, stability, organ selectivity, immunogenicity, and reproducibility.

Structural InstabilityRandom liquid-phase assembly risks payload loss during storage and administration.
Toxicity & ImmunogenicityIonizable lipids can trigger inflammatory markers.
Liver AccumulationNon-specific delivery limits access to extra-hepatic organs.
Manufacturing VariabilityBatch-to-batch variation complicates scale-up.
EnsaliX-Designed pLNPs

Nanoprecision-printed to enhance consistency, delivery performance, stability, and translational readiness.

More Stable StructuresSemi-solid patterned assembly improves structural consistency.
Self-Targeting DeliveryLigand-free architecture enables targeted delivery.
Improved Safety ProfileIonizable lipid-free design reduces immunogenicity.
High UniformityMillions of features patterned simultaneously.

Beyond the Liver

NanoPalm's delivery platform is engineered to enable extra-hepatic delivery — advancing precision treatment to tissues conventional systems can't easily reach.

Translucent human body highlighting extra-hepatic delivery reach of NanoPalm's platform

Partner With NanoPalm

We collaborate with biotech companies, pharmaceutical partners, academic researchers, and translational innovators to develop advanced therapeutics powered by NanoPalm's platform.

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